neuroanatomy Neuroanatomy is the study of the structure and organization of the nervous system. In contrast to animals with radial symmetry, whose nervous system consists of a distributed network of cells, animals with bilateral symmetry have segregated, defin ...

, the maxillary nerve (V) is one of the three branches or divisions of the

trigeminal nerve In neuroanatomy, the trigeminal nerve ( lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and chewin ...

, the fifth (CN V)

cranial nerve Cranial nerves are the nerves that emerge directly from the brain (including the brainstem), of which there are conventionally considered twelve pairs. Cranial nerves relay information between the brain and parts of the body, primarily to and ...

. It comprises the principal functions of

sensation Sensation (psychology) refers to the processing of the senses by the sensory system. Sensation or sensations may also refer to: In arts and entertainment In literature * Sensation (fiction), a fiction writing mode * Sensation novel, a Britis ...

from the

maxilla The maxilla (plural: ''maxillae'' ) in vertebrates is the upper fixed (not fixed in Neopterygii) bone of the jaw formed from the fusion of two maxillary bones. In humans, the upper jaw includes the hard palate in the front of the mouth. The t ...

nasal cavity The nasal cavity is a large, air-filled space above and behind the nose in the middle of the face. The nasal septum divides the cavity into two cavities, also known as fossae. Each cavity is the continuation of one of the two nostrils. The nasal c ...

sinuses Paranasal sinuses are a group of four paired air-filled spaces that surround the nasal cavity. The maxillary sinuses are located under the eyes; the frontal sinuses are above the eyes; the ethmoidal sinuses are between the eyes and the sphenoid ...

, the

palate The palate () is the roof of the mouth in humans and other mammals. It separates the oral cavity from the nasal cavity. A similar structure is found in crocodilians, but in most other tetrapods, the oral and nasal cavities are not truly sepa ...

and subsequently that of the mid-face, and is intermediate, both in position and size, between the

ophthalmic nerve The ophthalmic nerve (V1) is a sensory nerve of the face. It is one of three divisions of the trigeminal nerve (CN V). It has three branches that provide sensory innervation to the eye, the skin of the upper face, and the skin of the anterior sc ...

and the mandibular nerve.Illustrated Anatomy of the Head and Neck, Fehrenbach and Herring, Elsevier, 2012, page 180

Structure

It begins at the middle of the

trigeminal ganglion A trigeminal ganglion (or Gasserian ganglion, or semilunar ganglion, or Gasser's ganglion) is the sensory ganglion at the base of each of the two trigeminal nerves (CN V), occupying a cavity ( Meckel's cave) in the dura mater, covering the trige ...

as a flattened plexiform band then it passes through the lateral wall of the cavernous sinus. It leaves the skull through the

foramen rotundum The foramen rotundum is a circular hole in the sphenoid bone of the skull. It connects the middle cranial fossa and the pterygopalatine fossa. It allows for the passage of the maxillary nerve (V2), a branch of the trigeminal nerve. Structure T ...

, where it becomes more cylindrical in form, and firmer in texture. After leaving foramen rotundum it gives two branches to the pterygopalatine ganglion. It then crosses the

pterygopalatine fossa In human anatomy, the pterygopalatine fossa (sphenopalatine fossa) is a fossa in the skull. A human skull contains two pterygopalatine fossae—one on the left side, and another on the right side. Each fossa is a cone-shaped paired depression deep ...

, inclines lateralward on the back of the

, and enters the orbit through the

inferior orbital fissure The inferior orbital fissure is formed by the sphenoid bone and the maxilla. It is located posteriorly along the boundary of the floor and lateral wall of the orbit. It transmits a number of structures, including: * the zygomatic branch of the m ...

. It then runs forward on the floor of the orbit, at first in the infraorbital groove and then in the infraorbital canal remaining outside the periosteum of the orbit. It then emerges on the face through the

infraorbital foramen In human anatomy, the infraorbital foramen is one of two small holes in the skull's upper jawbone (maxillary bone), located below the eye socket and to the left and right of the nose. Both holes are used for blood vessels and nerves. In anatomica ...

and terminates by dividing into inferior palpebral, lateral nasal and superior labial branches. The nerve is accompanied by the infraorbital branch of (the third part of) the maxillary artery and the accompanying vein.

Branches

Its branches may be divided into four groups, depending upon where they branch off: in the cranium, in the pterygopalatine fossa, in the infraorbital canal, or on the face.

In the cranium

Middle meningeal nerve The middle meningeal nerve (meningeal or dural branch) is given off from the maxillary nerve (CN V2) directly after its origin from the trigeminal ganglion, before CN V2 enters the foramen rotundum. It accompanies the middle meningeal artery and ...

in the meninges

From the pterygopalatine fossa

Zygomatic nerve The zygomatic nerve is a branch of the maxillary nerve, itself a branch of the trigeminal nerve (CN V). It travels through the orbit and divides into the zygomaticotemporal and the zygomaticofacial nerve. It provides sensory supply to skin over ...

(

zygomaticotemporal nerve The zygomaticotemporal nerve (zygomaticotemporal branch, temporal branch) is a small nerve of the face. It is derived from the zygomatic nerve, a branch of the maxillary nerve (CN V2). It is distributed to the skin of the side of the forehead. It ...

zygomaticofacial nerve The zygomaticofacial nerve or zygomaticofacial branch of zygomatic nerve (malar branch) passes along the infero-lateral angle of the orbit, emerges upon the face through the zygomaticofacial foramen in the zygomatic bone, and, perforating the orbi ...

), through the

Inferior orbital fissure The inferior orbital fissure is formed by the sphenoid bone and the maxilla. It is located posteriorly along the boundary of the floor and lateral wall of the orbit. It transmits a number of structures, including: * the zygomatic branch of the m ...

Nasopalatine The nasopalatine nerve (long sphenopalatine nerve) is a nerve of the head. It is a branch of the pterygopalatine ganglion, a continuation from the maxillary nerve (V2). It supplies parts of the palate and nasal septum. Structure The nasopalati ...

nerve, through the

sphenopalatine foramen The sphenopalatine foramen is a Foramina of the skull, foramen in the skull that connects the nasal cavity with the pterygopalatine fossa. Structure The processes of the superior border of the palatine bone are separated by the ''sphenopalatine no ...

Posterior superior alveolar nerve The posterior superior alveolar branches (posterior superior dental branches) arise from the trunk of the maxillary nerve just before it enters the infraorbital groove; they are generally two in number, but sometimes arise by a single trunk. They ...

* Greater and

lesser Lesser, from Eliezer (, "Help/Court of my God"), is a surname. Notable people with the surname include: * Adolf Lesser (1851–1926), German physician * Aleksander Lesser (1814–1884), Polish painter and art critic * Anton Lesser (born 1952), Bri ...

palatine nerves *

Pharyngeal nerve The pharyngeal nerve is a small branch of the maxillary nerve, arising from the posterior part of the pterygopalatine ganglion. It passes through the palatovaginal canal with the pharyngeal branch of the maxillary artery, and is distributed to th ...

In the infraorbital canal

Middle superior alveolar nerve The middle superior alveolar nerve is a nerve that drops from the infraorbital portion of the maxillary nerve to supply the sinus mucosa, the roots of the maxillary premolars, and the mesiobuccal root of the first maxillary molar. It is not al ...

Anterior superior alveolar nerve The anterior superior alveolar nerve (or anterior superior dental nerve), is a branch of the infraorbital nerve, itself a branch of the maxillary nerve (V2). It branches from the infraorbital nerve within the infraorbital canal before the infraorbi ...

Infraorbital nerve The infraorbital nerve is a branch of the maxillary nerve, itself a branch of the trigeminal nerve (CN V). It travels through the orbit and enters the infraorbital canal to exit onto the face through the infraorbital foramen. It provides sensory ...

On the face

Inferior palpebral nerve The Inferior palpebral nerve (inferior palpebral branches) ascend behind the orbicularis oculi. They supply the skin and conjunctiva of the lower eyelid, joining at the lateral angle of the orbit with the facial and zygomaticofacial nerve The zyg ...

Superior labial nerve The superior labial branches (labial branches), the largest and most numerous, descend behind the quadratus labii superioris, and are distributed to the skin of the upper lip, the mucous membrane of the mouth, and labial glands. They are joined, i ...

*Lateral nasal nerve

Function

The Maxillary nerve gives cutaneous branches to the face. It also carries parasympathetic preganglionic fibers (sphenopalatine) and postganglionic fibers (zygomatic, greater and lesser palatine and nasopalatine) to and from the pterygopalatine ganglion.

Additional Images

File:Slide9nnn.JPG, Maxillary nerve

References

Books

# *

External links

* * () {{Authority control